Drug Delivery for Enhanced Bioavailability of BCS2 (Poorly Soluble) Compounds

Drug Delivery for Enhanced Bioavailability of BCS2 (Poorly Soluble) Compounds
Product Description

Engineered to bring together advanced silica technologies with challenging active pharmaceutical ingredients (APIs) to effectively formulate a large class of poorly soluble but otherwise promising compounds, Grace’s SILSOL® silica-based drug delivery technology provides solutions for poorly soluble active ingredients. Combining our expertise in mesoporous silica gel, novel application methods, and patented technologies, SILSOL® silica can provide solutions for acceleration of the screening and development of solubility enhancing solid dispersions, with the added benefit of doing so with compendial, scalable, and available silicas.

Grace GmbH

  • DE
  • 2022
    On CPHI since
  • 1000 - 4999
    Employees
Company types
Manufacturer/Innovator

Grace GmbH

  • DE
  • 2022
    On CPHI since
  • 1000 - 4999
    Employees
Company types
Manufacturer/Innovator

More Products from Grace GmbH (5)

  • SYLOID® mesoporous silicas and VYVID™ superparamagnetic silicas

    Product SYLOID® mesoporous silicas and VYVID™ superparamagnetic silicas

    SYLOID® FP mesoporous silica is the ideal choice for formulations due to its unique morphology to help improve the handling, adsorption, and dissolution of many pharmaceuticals. - Effective desiccant to increase the stability of moisture-sensitive APIs - Efficient conditioner for powder formulations use...
  • Custom Fine Chemical Manufacturing

    Product Custom Fine Chemical Manufacturing

    Our comprehensive portfolio of services, integrated manufacturing, and regulatory leadership differentiates us as a leading contract development and manufacturing partner. With a proven ability to deliver solutions to complex challenges, Grace’s FCMS supports the entire small molecule development cycle fro...
  • Generic APIs

    Product Generic APIs

    Grace's Fine Chemical Manufacturing Services (FCMS) has a long history of supplying high-quality generic and custom APIs to the pharmaceutical and nutraceutical markets. Grace's FCMS has manufactured some of the most notable APIs that are now part of our portfolio of generic products available to devel...
  • Multifunctional Excipients for the Nutraceutical and Pharmaceutical Industry

    Product Multifunctional Excipients for the Nutraceutical and Pharmaceutical Industry

    Our SYLOID® FP silica excipients are a strategic drug development tools in today’s challenging pharmaceutical industry with its demands for improved formulations, bringing new drugs to market faster, and technological advances.

    SYLOID® FP silica’s unique, innovative design combine...
  • Custom Bonding and Chromatography Resins for Small and Large Molecule Purification

    Product Custom Bonding and Chromatography Resins for Small and Large Molecule Purification

    Grace offers high quality chromatography silica resins with a wide range of pore diameters, particle sizes, and chromatography phases. We provide custom bonding of silica (30Å-4500Å; 5µm to 200µm) for different reversed and normal phases, ion exchange, and other chemistries. We develop and manufacture ...

Grace GmbH resources (3)

  • Brochure Pharmaceutical Solutions

    W. R. Grace & Co.’s history of exceeding customer expectations is built upon our unyielding commitment to innovation and advancement of technical expertise, which is reflected throughout the drug development process.

    Grace’s Portfolio for Pharmaceutical Solutions Includes:


    Fine chemicals synthesis expertise
    Decades of experience in organic chemical synthesis at our fully integrated North American sitesUnique multifunctional excipients 
    SYLOID® multifunctional excipientsSILSOL® silica active ingredient delivery technologyHighly efficient chromatography resins 
    DAVISIL® silica, VYDAC® chromatography resins, and VYKING™ superparamagnetic silica
  • Brochure Grace’s Fine Chemical Manufacturing Services (FCMS)

    Grace’s Fine Chemical Manufacturing Services (FCMS) has the facilities and expertise to support product development at every stage, from contract research through commercial manufacturing. Having the appropriate resources where you need them, when you need them is critical, and our multiple locations and deep experience can help ensure your success.
  • Brochure SYLOID® FP Silica: Multifunctional Excipients for the Nutraceutical and Pharmaceutical Industry

    SYLOID® FP silica’s unique, innovative design combines adsorption capacity, particle size, density, and internal surface area to provide multifunctional benefits or optimize an application. This helps minimize the number of excipients used and the complexity of formulations while expediting manufacturing, ultimately improving the efficacy of the final dosage form.