DOPAMINE S.A.L.F.

Dopamine acts as an agonist on specific dopamine receptors and on alpha and beta adrenergic receptors. It decreases peripheral resistance and causes mesenteric and renal vasodilation. It increases renal blood flow, glomerular filtration and urinary flow. As regards the heart, dopamine causes an increased inotropism. It differs from noradrenaline in the action on the region of the kidneys and from isoproterenol, as it does not increase the heart rate. The knowledge about cardiovascular activities of dopamine involving the activation of alpha and beta adrenergic receptors, as well as dopaminergic receptors, allows to better modulate the amine infusion, which, depending on the dose, can give effects of vasoconstriction or vasodilation, cardiac stimulation, inhibition of the increase in heart rate, diuresis, natriuresis and inhibition of aldosterone circulation. SALF is also committed to the development of two new concentrations, 200mg/5ml and 400mg/5ml.