Diosmin

Diosmin is a semisynthetic phlebotropic drug,a member of the flavonoid family.It is used with Hesperidin to control internal symptoms of hemorrhoids(piles).It is an oral phlebotropic drug used in the treatment of venous disease,ie,chronic venous insufficiency(CVI)and hemorrhoidal disease(HD),in acute or chronic hemorrhoids,in place of rubber-band ligation,in combination with fiber supplement,or as an adjuvant therapy to hemorrhoidectomy,in order to reduce secondary bleeding.

Diosmin prolongs the vasoconstrictor effect of noradrenaline on the vein wall,increasing venous tone,and therefore reducing venous capacitance,distensibility,and stasis.This increases the venous return and reduces venous hyperpressure present in patients suffering from CVI.