Combination Products

Combination Products
Product Description

A combination product is the combination of a physical part and a drug which can be implanted or worn on the body for long-term treatments. Combination products offer several advantages when compared with drug delivery via oral, injection, and infusion methods: 

Controlled release of the Active Pharmaceutical Ingredients (API): the controlled release as opposed to the bolus-type delivery facilitates consistent API concentrations within an optimal therapeutic range 

Targeted delivery of the API: this strength of drug-eluting devices, particularly implanted devices, permits higher therapeutic dosages to be delivered while minimizing adverse side effects 

Improved Patient Compliance: combination products improve patient compliance and most healthcare practitioners agree that within an aging population, compliance becomes less certain and therefore more important 

Prevention of infection: an API added to a device can improve the device function and help to prevent local, as well as systemic infection 

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Trelleborg Healthcare & Medical

  • FR
  • 2021
    On CPHI since
  • 2
    Certificates
  • 5000+
    Employees
Company types
Drug delivery device Supplier/Manufacturer
Engineering
Machinery and Equipment Supplier/Manufacturer
Primary activities
Biopharmaceutical
Contract Manufacturer
Medical Devices
View company profile
Categories
more categories Show less

Trelleborg Healthcare & Medical

  • FR
  • 2021
    On CPHI since
  • 2
    Certificates
  • 5000+
    Employees
Company types
Drug delivery device Supplier/Manufacturer
Engineering
Machinery and Equipment Supplier/Manufacturer
Primary activities
Biopharmaceutical
Contract Manufacturer
Medical Devices
View company profile

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  • Introducing APIs to Silicone & Controlling Elution Rates

    Whitepaper Introducing APIs to Silicone & Controlling Elution Rates

    Our Trelleborg Healthcare & Medical experts have placed an emphasis on serving our partners developing drug-eluting devices and implantable drug delivery systems because of the potential these technologies have to provide innovative therapies for patients.

    In an effort to build confidence in these therapeutic forms our team presents the information that has led to our excitement about the technology as well as a detailed recap of experiments we’ve conducted along with a summary of learnings we’ve gathered as a result.Key Takeaways: 

    An understanding of the market trends supporting increased developmentFamiliarity with the early uses of drug elution as well as our expectations on where it will goExcipient materials used as well as the manufacturing methods that can be employedA detailed breakdown of multiple ways APIs can be introduced to siliconeA better view of alternative methods for introducing APIs to silicone via several case studies presented<