Polyglykol: Use as API for Laxative Formulations

In today’s world, medical innovations and pharmaceutical technology are essential drivers of human health: they open up the possibility of new treatments and subsequently act as a gateway which allows people around the world to access new medicines, improving their quality of life.

In the production of pharmaceuticals, high-quality ingredients play a crucial role and must meet ever-increasing expectations in quality assurance to guarantee that safe, effective medicines reach the end consumer.

Clariant Health Care is a leading high-quality solution partner for the global pharmaceutical industry, with a strong portfolio of top-performing excipients and active pharmaceutical ingredients (APIs), backed by operational excellence and years of experience in regulatory affairs.

Explore Clariant’s high functional excipients to enable APIs bioavailability enhancement, controlled release, target delivery, stabilization, continuous manufacturing, preservation and viscosity enhancement.


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This session was originally broadcast as part of the CPHI Worldwide 2021 digital content programme. Non-ionic solubilizers based on polysorbates, castor oil derivatives and poloxamer provide well established safety track record due to numerous OTC, Rx and dietary supplement products available on market. For formulators these classical solubilizers are first choice of excipients to improve the solubility and bioavailability of poorly soluble APIs. The non-ionic solubilizers are proven very effective starting from simple o/w kind of formulations to innovative applications such as SEDDS, hot melt extrusion, spray drying etc. to improve the bioavailability of APIs. This session discusses: Non-ionic solubilizers (VitiPure™ L 20, VitiPure™ O 80, VitiPure™ HCO 40, VitiPure™ CO 35, VitiPure™ P 188) to improve solubility and bioavailability of poorly soluble APIs Well established safety & toxicology via several marketed drugs world-wide Proven effective for all routes of administration and various pharmaceutical dosage form

This session was originally broadcast as part of the CPHI Worldwide 2021 digital content programme. Low molecular weight Polyethylene glycols 300 & 400 are commonly used in formulations as solvents for APIs which are not soluble in water. For high-risk applications, stringent control of microbial load is essential. VitiPure™ LEX 300 and VitiPure™ LEX 400 offer relevant product specifications making them suitable for high-risk applications. This session explores: Low molecular weight PEG 300 (VitiPure™ LEX 300) and PEG 400 (VitiPure™ LEX 400) with Low microbial load for high-risk applications Surpass the current pharmacopoeia requirements Microbiological specifications support risk assessment in pharmaceutical and biopharmaceutical manufacturing

Clariant Polyethylene Glycols / Macrogols use as Excipients for multiple Applications

Clariant Motusflex range use as Excipients for Topical applications.

Clariant VitiPure range use as Excipients for multiple applications. Bioavailability Enhancement of Poorly Soluble APIs. A wide solubilizers offering

Effective and high-purity ingredients including a complete range of  Polyglykols (Macrogols) our universally applicable pharmaceutical polymers, with various molecular weights, supported by CEP certification and DMF type II documentation.

Bioavailability Enhancement of Poorly Soluble APIs - A wide solubilizers offering