Cellerant Starts Leukaemia Drug Trial
The drug trial will assess the safety and tolerability of CLT-008 in the setting of chemotherapy-induced neutropenia.
Cellerant Therapeutics has launched a Phase I/II clinical trial of CLT-008 in patients receiving intensive post-remission chemotherapy for high-risk leukaemia or myelodysplasia. The open-label, multicentre, dose escalation trial will assess the safety and tolerability of CLT-008 in the setting of chemotherapy-induced neutropenia.
The trial will enroll approximately 30 evaluable patients with high-risk acute myelogenous leukaemia, acute lymphoblastic leukemia (ALL/AML), chronic myelogenous leukaemia (CML) or myelodysplasia (MDS).
The secondary objective includes efficacy-related endpoints such as time to neutrophil recovery, duration of severe neutropenia and thrombocytopenia, days of fever and incidenc
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