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28 Jun 2011

BMS & AstraZeneca Reports Positive Data for Diabetes Treatment

BMS and AstraZeneca reported positive data from a Phase III clinical study evaluating their investigational sodium-glucose co-transporter-2 (SGLT2) inhibitor dapagliflozin, combined with metformin, for the treatment of type 2 diabetes.

The American Diabetes Association (ADA) meeting in San Diego included the presentation of new data from Phase III trials evaluating Bristol-Myers Squibb (BMS) and AstraZeneca’s dapagliflozin

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BMS and AstraZeneca reported positive long-term data from a Phase III clinical study evaluating their investigational sodium-glucose co-transporter-2 (SGLT2) inhibitor dapagliflozin, combined with metformin, for the treatment of type 2 diabetes. Data from the trial showed that the dapagliflozin-metformin combination maintained reductions in HbA1c levels from 52-weeks to 104-weeks, compared with combination therapy using the sulfonylurea glipizide and metformin.

 

The study data also confirmed that patients treated with dapagliflozin added to metformin experienced 10 times less frequ

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