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Bazedoxifene (acetate)

Bazedoxifene (acetate)
Product Description

The mechanism of action of bazedoxifene acetate is unique. It is a novel selective estrogen receptor modulator (SERM) that selectively regulates estrogen receptors. Bazedoxifene acts as an estrogen receptor agonist in certain tissues of the body. In human bones, it has the same effect as estrogen (estrogen can delay bone aging and reduce the incidence of fractures).

Shanghai Haoyuan ChemExpress Co., Ltd.

  • CN
  • 2022
    On CPHI since
  • 3
    Certificates
  • 1000 - 4999
    Employees
Company types
CMO/CDMO
Contract Research Organisation (CRO)
Primary activities
Analytical Services
Contract Manufacturer
Contract Research Organisation
Custom Manufacturing/Custom Synthesis
Generic APIs producer
Intermediates Manufacturer
Specifications
  • CAS Registry Number
    198481-33-3
  • Details
    Bazedoxifene acetate (TSE-424 acetate) is an orally active, nonsteroidal selective estrogen receptor modulator (SERM) with IC50 values of 23 nM and 99 nM for ERα and ERβ, respectively. It can be used for the research of osteoporosis. Additionally, bazedoxifene acetate acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer.

Shanghai Haoyuan ChemExpress Co., Ltd.

  • CN
  • 2022
    On CPHI since
  • 3
    Certificates
  • 1000 - 4999
    Employees
Company types
CMO/CDMO
Contract Research Organisation (CRO)
Primary activities
Analytical Services
Contract Manufacturer
Contract Research Organisation
Custom Manufacturing/Custom Synthesis
Generic APIs producer
Intermediates Manufacturer

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