Bayer & Onyx Initiate Phase III Trial for Breast-cancer Drug
Bayer and Onyx Pharmaceuticals have started recruiting breast-cancer patients to start the third stage of testing their Nexavar pill, a key pipeline drug for both drugmakers.
Bayer HealthCare and Onyx Pharmaceuticals, Inc. announced that the companies have started the enrollment of patients in a Phase III randomized, double-blind, placebo-controlled trial evaluating Nexavar? (sorafenib) tablets in combination with the oral chemotherapeutic agent, capecitabine, versus placebo plus capecitabine for the treatment of patients with advanced breast cancer.
This Phase III trial was initiated based on the results from a cooperative group-sponsored Phase II clinical trial evaluating Nexavar in combination with capecitabine in patients with advanced breast cancer.
"This Phase III trial is an important milestone in our development of Nexavar as it provides an opportunity to validate the promising Phase II results," said Dr.
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