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13 Oct 2015

BASF introduces: Kollicoat IR — the binder of choice for peroxide sensitive API formulations

A powerful binder designed to avoid peroxide formation.

The formulation of peroxide sensitive active ingredients (API) is a growing topic. Not only novel APIs are often subject to peroxide-induced deterioration, also reformulation or repacking of existing APIs for increased patient compliance often faces the issue of potential peroxide interaction caused by the binder used.

Kollicoat IR is a true multi-talent. Thanks to its clever design, it has additionally to its instant release coating functionality successfully proven its capability as tablet binder in various commercial products by combining strong binding performance with an easy processing and the unique characteristic of no peroxide formation:

  • Binding performance comparable to polyvinylpyrollidone (PVP), superior to HPMC
  • Easy processing due to low viscosity in solution
  • No peroxide formation at any time
  • The combination of these characteristics provides new possibilities in the formulation of peroxide sensitive active ingredients and additionally provides significant design space for lifecycle management of existing drugs. Meet our experts at CPHI worldwide – Hall 7, Booth 7H30

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