ATB-330

Product Description

[ALK5 inhibitor / Small Molecule / Develop for IPF and Fibrosis) – Complete to derivate the lead compound

1. Confirm the highest ALK5 selectivity with superior efficacy and PK profile through in-vivo tests compared to competitors (small molecule new drugs)

2. For IPF treatment, develop as inhalation therapy to avoid systemic exposure and minimize possible toxicities
- ALK5 inhibitor projects are dropped due to the side effects such as hepatotoxicity, skin toxicity, and cardiotoxicity through systemic circulation in clinical trials

3. Confirm the superior efficacy compared to the standard therapy of IPF through in-vivo tests

Autotelic Bio

KR
2021

On CPHI since
25 - 49

Employees

Company types

Manufacturer/Innovator

Compare Add to favorites Added to favorites

Autotelic Bio

KR
2021

On CPHI since
25 - 49

Employees

Company types

Manufacturer/Innovator

Compare Add to favorites Added to favorites

More Products from Autotelic Bio (2)

Product ATB-101

[ARB+SGLT-2i Fixed Dose Combination] – In process of Phase 3 clinical trial on approx. 250 patients
1. The first Fixed Dose Combination treating hypertension and type 2 diabetes by a tablet in the world

2. Expect the synergistic effect in the treatment of hypertension though mi...

Compare
Product ATB-301

[TGF-β2 Targeting ASO (TASO) + IL-2 Combination therapy] - Phase Ib

1. Confirm the potential of TGF-β2 as a biomarker in human blood and tumor tissues from the efficacy result of Phase Ib clinical trial on cancer patients

2. Confirm the suppression of IL-2’s side effect in combinati...

Compare

Autotelic Bio resources (1)

Brochure Autotelic Bio's Brochure

We have several pipelines under deveopment

Oncology
ATB-301
ATB-320

Fixed Dose Combination
ATB-101

Recommended Products

Product Enzalutamide

Enzalutamide API
Monthly capacity: customized
Package size: 25kg/drum
Appearance: white solid
Purity: ≥99%
Max single impurity: ≤0.1%
Product Ixazomib Citrate

Indicated in combination with lenalidomide and dexamethasone for the treatment of patients with multiple myeloma who have received at least one prior therapy.
Product Dexrazoxane

Oncology drugs/adjuvant antitumor drugs.CAS NO.24584-09-6,
Standard: In-house
Product Cyclopropane Carboxylic Acid

Trinexapac-ethyl intermediates
Product Walk in Cooling Cabinet.

The Walk-In Cooling Cabinets / cold rooms are designed according to ICH guidelines, WHO, MCA and USFDA requirements to maintain uniform conditions. They are superior in airflow distribution, temperature control technology, cabinet construction and are manufactured as per cGMP regulations.
Biggest Walk...
Product AZACITIDINE - AMILIX 100 MG

Single use vial ampoule containing azacitidine 100 mg freeze dried powder for IV/SC infusion. Antineoplastic, DNA Methylation Inhibitor
Product Cyclophosphamide Monohydrate

A niche oncology API used for the treatment of malignant lymphomas (Stages III and IV of the Ann Arbor staging system), Hodgkin's disease, lymphocytic lymphoma (nodular or diffuse), mixed-cell type lymphoma, histiocytic lymphoma, Burkitt's lymphoma. multiple myeloma.. Available for all global markets ex...
Product test-2

tst-2
Product RayDyLyo® Vial adapter

ARaymondlife has developed the essential accessory for drug reconstitution, the vial adapter, one for each RayDyLyo diameter. The RayDyLyo® vial adapter is a medical device intended for the quick and safe reconstitution of drugs, contained in vials capped with RayDyLyo® plastic press fit caps, a...
Product FPFs

• Genexol®PM Inj.(Paclitaxel) • Genexol® Inj.(Paclitaxel) • Nanoxel®M Inj.(Docetaxel) • Docetaxel Inj.(Docetaxel) • Nexatin® Inj.(Oxaliplatin) • Everose® Tab.(Everolimus) • Pemed®S Inj.(Pemetrexed) • Azalid® Inj.(Azacitidine) • Decilid® Inj.(Decitabine) • Lenalid® Inj.(Lenalid...
Product [13C4, 15N2]-5-Fluorouracil

5-Fluorouracil is one of the most administrated drugs for the treatment of solid cancers.The use of this drug induces severe toxicities caused mainly by the deficiency of the enzymedihydropyrimidine dehydrogenase (DPD), therefore a pretreatment assessment is necessary. MW: 136,03 g.mol-1 Formula: C4H3FN2O2...
Product Our Privated Product ( Oncology API)

• 1.Azacitidine • 2.Bortezomib • 3.Pemetrexed Disodium • 4.Carfilzomib 5.Trabectedin
Product SABU-100

Sildenafil Citrate 100 mg Tablets B.P
Product AROMATHERAPY OILS

AOS Products Pvt Ltd have a commitment to bring human closer to nature so that all can be benefited by it. Most of the essential Oils are therapeutic in nature, Only the aroma of these oils helps to cure several disorders and diseases. Thus we try hard to keep the natural therapeutic quality of the oil so ...
Product INJECTIONS

Albumin bound Paclitaxel Inj Azacitadine Inj Bendamustin Inj Bortezomib Inj Busulfan Inj Carboplatin Inj Carfilzomib Inj Carmustin Inj Cisplatin Inj Cytrabine Inj Dacarbazine Inj Dactinomycin Inj Degrarelix Inj Doceteaxel Inj Doxorubicin Inj Epirubicin Inj Eribulin Inj Etoposide Inj Fludarabine Inj Fosapre...
Product Belloxa - Oxaliplatin

Composition Oxaliplatin 50 mg &100 mg

Indication
Adjuvant treatment of stage III colon cancer (Duke stage C) after complete resection of initial tumor, treatment of metastatic colorectal cancer
Product Dasatinib anhydrous/monohydrate

We offer a wide range of API products which include Dasatinib monohydrate and Dasatinib anhydrous. It belongs to oncology category. Therapeutic category: molecular targeted. Regulatory status for Dasatinib monohydrate:USDMF No. 23763, USFDA Approved, Stability Studies Zone IVB, WC available ...
Product Bortezomib Injection 3.5 mg vial (Bortezomib)

It is an anti-cancer medication used to treat multiple myeloma and mantle cell lymphoma
Product Paclitaxel

Paclitaxel belongs to the category of chemotherapeutic agents and is utilized as a treatment for various types of cancer. Indications for using paclitaxel encompass a range of cancers, including breast, ovarian, bladder, lung, prostate, melanoma, esophageal, Kaposi sarcoma, and various other solid tumors.
Product Oxaliplatin

Oxaliplatinis a cancer medication used to treat colorectal cancer. Often it is used together with fluorouracil and folinic acid (leucovorin) in advanced cancer.

For more information about our made in Germany product, please contact us. pharma@axxo.de
...
Product PBD Core™

Advanced intermediate.Enables rapid synthesis of PBD payloads.Suitable for up to phase I clinical studies with process, validation to support path to commercial approval.Contact one of our experts to request a free sample
Product DolCore™

Advanced intermediateEnables rapid synthesis of dolastatin-10 payloads.Suitable for up to phase I clinical studies with process, validation to support path to commercial approval.Contact one of our experts to request a free sample.
Product Bicalutamide capsules

50mg daily: Combination with luteinizing hormone releasing hormone (LHRH) analogs or surgical orchiectomy for the treatment of advanced prostatic carcinoma.

150mg daily: For the treatment of patients with locally advanced prostate cancer without distant metastasis, who are unsuitable or unwillin...
Product BENDAMUSTINE

Bendamustin is a chemotherapy medication used in the treatment of chronic lymphocytic leukemia (CLL), multiple myeloma, and non-Hodgkin's lymphoma.[2][3] It is given by injection into a vein.
Product Binimetinib

Indicated, in combination with encorafenib, for the treatment of patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation
Product BORTEZOMIB - BROMADENE 3.5 MG

Vial ampoule of freeze dried powder containing Bortezomib 3.5 mg for IV injection
Product Cabazitaxel EVER Pharma: 45mg/4.5ml + 50mg/5ml + 60mg/60ml - Single liqu...

Cabazitaxel EVER Pharma is provided as a single vial, ready to dilute formulation and is available in vial sizes covering the common range of patient specifi c doses for economy and convenience Cabazitaxel is a third-generation antineoplastic taxane and was the fi rst therapy to show a survival benefi t f...
Product Cyclopropyl carbinol

intermediates
Product Cisplatin

Heraeus Precious Metals business line Pharmaceutical Ingredients provides a wide range of active pharmaceutical ingredients, which includes Cisplatin. Contact us for more information.
Product Carmustine

A niche oncology API used in its finished form (injectable) for the treatment of brain tumors glioblastoma, brainstem glioma, medulloblastoma, astrocytoma, ependymoma, and metastatic brain tumors. Available for all global markets except the US along with DMF support.
Product Pemetrexed EVER Pharma

Pemetrexed is an antineoplastic chemotherapy drug. It is used in the treatment of malignant mesothelioma and locally advanced or metastatic nonsquamous non-small cell lung cancer. - Available as a ready to dilute liquid formulation - does not require reconstitution from powder saving time and costs. It can...
Product MayCore™

Advanced intermediateEnables rapid synthesis of maytansine payloads.Suitable for up to phase I clinical studies with process, validation to support path to commercial approval.Contact one of our experts to request a free sample.
Product Carboplatin

Heraeus Precious Metals business line Pharmaceutical Ingredients provides a wide range of active pharmaceutical ingredients, which includes Carboplatin. Contact us for more information.
Product Docetaxel anhydrous

We offer a wide range of API products which includes Docetaxel anhydrous. It belongs to oncology category. Therapeutic category: antineoplastic.

Other products:Amisulpride，Desvenlafaxine Succinate，Neostigmine methylsulfate
Teicoplanin，Daptomycin，Minocycline HCl，Vancomycin HCl, Levofloxacin...
Product Midostaurin

Indicated, in combination with standard cytarabine and daunorubicin induction and cytarabine consolidation chemotherapy, for the treatment of adult patients with newly diagnosed acute myeloid leukemia (AML) who are FLT3 mutation-positive, as detected by a FDA approved test
Product Trabectedin EVER Pharma: 0.25mg + 1.0mg - LYO Vial

- Available in 2 presentations – providing greater flexibility and convenience when preparing patient specific doses - All vial sizes come in CytoWrap® – for safer handling and transportation Description: Trabectedin is an antineoplastic chemotherapy drug. It is indicated as a monotherapy for the treatme...
Product Fluorouracil

Fluorouracil is a medication used to treat cancer. By injection into a vein it is used for colon cancer, esophageal cancer, stomach cancer, pancreatic cancer, breast cancer, and cervical cancer. As a cream it is used for actinic keratosis, basal c...
Product Oxaliplatin

Heraeus Precious Metals business line Pharmaceutical Ingredients provides a wide range of active pharmaceutical ingredients, which includes Oxaliplatin. Contact us for more information.
Product EVER Pharma: Product Portfolio

Our products include: • Atosiban • Cabazitaxel • Cerbrium • Cerebrolysin • Dacepton/Apomorphine • Dexemedetomidine • Docetaxel • Fulvestrant • MemoProve • Oxytocin • Paclitaxel • Pemetrexed • Tachyben • Terlipressin • Trabectedin • Eribulin
Product TAMOXIFEN CITRATE

TAMOXIFEN CITRATE is a medication that is used to prevent breast cancer in women and treat breast cancer in women and men. It is also being studied for other types of cancer. It has been used for Albright syndrome.For more information about our made in Germany product, please cont...
Product Exatecan

A GMP quality payload for your drug-conjugateprogram• Samples available free of charge• Validated analytical methods• Free licensing and no royalty payments
Product Carboplatin

Carboplatin is is a chemotherapy medication used to treat a number of forms of cancer. This includes ovarian cancer, lung cancer, head and neck cancer, brain cancer, and neuroblastoma.

For more information about our made in Germany product, please contac...
Product Precious Metal Catalysts

Heraeus Precious Metals offers a wide range of homogeneous and heterogeneous precious metal catalysts, enabling numerous chemical reactions. Contact us for more information.
Product ChetoSensar™

ChetoSensar™ is our novel solubilization technology for hydrophobic ADCs.

Increased ADC solubility, important for reaching high DARWider therapeutic index and higher drug efficacyImproved bioconjugation efficiencyChetoSensar™ and ready-to-conjugate drug linkers available as samples or within ADC...
Product CDMO

• Cytotoxic Injection (Liquid , Lyophilized) • ONCOLOGY • CYTOTOXIC API • EU GMP • JGMP (Japan) • KGMP (Korea) • PIC/S
Product Melphalan HCl

A niche oncology API used for the treatment of multiple myeloma and ovarian cancer. Melphalan HCl Injection, at high intravenous dosage, is indicated, with or without haematopoietic stem cell transplantation, for the treatment of multiple myeloma and childhood neuroblastoma. Available for all global mar...
Product Arsenic

Heraeus Precious Metals business line Pharmaceutical Ingredients provides a wide range of active pharmaceutical ingredients which includes Aresenic. Contact us for more information.
Product MMAE

A GMP quality payload for your drug-conjugateprogram• Samples available free of charge• Validated analytical methods• Free licensing and no royalty payments
Product Thiotepa

Heraeus Precious Metals business line Pharmaceutical Ingredients provides a wide range of active pharmaceutical ingredients, which includes Thiotepa. Contact us for more information.