Aprotinin

Aprotinin
Product Description

Aprotinin, a single-chain polypeptide of 58 amino acids, is also known as basic pancreatic trypsin inhibitor (BPTI) or trypsin-kallikrein inhibitor. It slows fibrinolysis, preserves platelet function, and has anti-inflammatory effects.

Pentapharm produces Aprotinin API for various indications:

- Cardiac Surgery: Used prophylactically to reduce blood loss and transfusions in high-risk patients.

- Fibrin Sealant: Added to fibrin glue to stabilize fibrinogen and thrombin components by delaying fibrinolysis.

- Biopharmaceutical Processes: Used to isolate proteins and prevent degradation during cell and tissue lysis by inhibiting serine proteases like trypsin, plasmin, and others

Read more Show less

Pentapharm AG

  • CH
  • 2023
    On CPHI since
  • 4
    Certificates
  • 100 - 249
    Employees
Company types
CMO/CDMO
Manufacturer/Innovator
Primary activities
API Producer
Contract Manufacturer
Generic APIs producer
View company profile
Categories
more categories Show less
Specifications
  • CAS Registry Number
    9087-70-1
  • Details
    Aprotinin Concentrated Liquid 
    MW: 6512 g/ mol
    50ml, 1000ml
  • Selling Points
    Cardiovascular Health; International Approvals/Standards; Product Features; Product Performance; Quality Service; cGMP QualityRegistrations incl. DMF, etc.
  • Model
    Article number 073-70
  • Supplied from
    Switzerland
More specifications Fewer specifications
Sales Markets
Show more Show less

Pentapharm AG

  • CH
  • 2023
    On CPHI since
  • 4
    Certificates
  • 100 - 249
    Employees
Company types
CMO/CDMO
Manufacturer/Innovator
Primary activities
API Producer
Contract Manufacturer
Generic APIs producer
View company profile

More Products from Pentapharm AG (3)

  • Batroxobin

    Product Batroxobin

    Defibrase® is Pentapharm's trademark for Batroxobin, a serine protease and thrombin-like enzyme from Bothrops moojeni snake venom. Unlike thrombin, batroxobin only splits fibrinopeptide A from fibrinogen, causing a defibrinogenating effect.

    Batroxobin is clinically used to treat thromboti...
  • Haemocoagulase

    Product Haemocoagulase

    Reptilase® is Pentapharm's trademark for Haemocoagulase, a purified enzyme system from Bothrops atrox snake venom. This system is toxin-free and includes two enzymes that aid coagulation:

    - A thrombin-like serine protease that cleaves fibrinogen to produce Fibrinopeptide A and Fibrin I mo...
  • Prionex®

    Product Prionex®

    Prionex® is a 10% aqueous solution of highly purified dermal collagen from porcine origin, known for its excellent protein-stabilizing properties. It is partially hydrolyzed, terminally sterilized, and free from cartilage, bone, and plasma components.

    Key Advantages:

    - Opti...