APOLACT® Nasale TDC spray

APOLACT Nasale TDC spray is a medical device class I. It contains a mixture of apolactoferrin and lactoferrin in liposomes with sorbitol specially designed for hygiene, hydration and protection of the nasal cavity. Liposomes are lipid spheres that allow the protection and release of Apo-lactoferrin. LTF is an iron-chelating glycoprotein, that defends the human body against a wide range of pathogens. The antimicrobial and anti-inflammatory properties of lactoferrin are largely due to its ability to bind free iron Fe3 +, an essential cofactor for microbial growth and for the production of free radicals. The antiviral effect of lactoferrin is related to its ability to bind to plasma membrane glycosaminoglycans, preventing the virus from entering and stopping infection in the bud. Apolactoferrin (iron-free form of lactoferrin) is more active than lactoferrin itself (5 times) since the bond with iron is achieved in the open form of apoprotein, allowing easier access to Fe³ + ions.