Amgen & UCB to Conduct Sclerostin Antibody Test in NASA Shuttle

Amgen and UCB are working with NASA Ames Research Center to conduct a preclinical test of a sclerostin antibody in an experiment aboard space shuttle Atlantis.

Amgen and UCB are collaborating with the National Aeronautics and Space Administration (NASA) Ames Research Center to conduct a preclinical test of a sclerostin antibody in an experiment that will take place aboard space shuttle Atlantis scheduled to launch July 8, 2011.

The loss of bone mass during space flight remains a significant problem for human space missions, especially long-term flights. This experiment will assess the effect of a sclerostin antibody on the loss of bone associated with space flight in mice. In this experiment of 30 space-flown mice, half of the mice are given the sclerostin antibody and the remaining mice receive a placebo.

After the flight, various aspects of the structure, composition, strength, and cell and molecular n