Alaptide

Alaptide
Product Description

Alaptide enables a significant stimulating effect of human diploid cells (LEP-19) without transformation changes in their morphology. This effect can be used in various areas of regenerative medicine, such as treating burn injuries, skin treatment etc. Epidermal regeneration abilities of Alaptide was also proved on a number of tests using domestic pigs. It was found out that Alaptide causes a faster skin regeneration of various injuries. Moreover, Alaptide is also used as a modifier of permeation through the stratum corneum (SC), the least permeable layer of skin. Even though Alaptide is almost insoluble in water (0.1104 g/100 mL), they are physical ways (such as milling with various emulsifiers and stabilisers) how to increase its solubility and, therefore, the ability of permeation. This highly soluble modified Alaptide can be efficiently used as a transdermal permeation modifier, i.e. as pharmaceutical adjuvant (excipient), in pharmaceutical formulations, such as oleo-ointments, hydro-ointments, oleo-creams, hydro-creams, gels or transdermal therapeutic systems, where it influences the absorption/permeation of various compounds into the skin and/or through the skin, increasing their concentration at the place of administration and/or their systemic concentration. Interestingly, it was originally developed and tested for its nootropic effects with possible oral administration. Alaptide at Santiago Lab At Santiago Lab, we have been working intensively on the research of this unique molecule. We managed to replicate the original synthesis and significantly improve it for our conditions and large scale preparation. Thanks to that, we can now synthesise this molecule in an excellent purity on a kg scale for more than a competitive price.

Santiago Chemikalie

  • CZ
  • 2023
    On CPHI since
  • 1 - 24
    Employees
Company types
Contract Research Organisation (CRO)
Contract Service
Primary activities
Chemical Development
Contract Manufacturer
Contract Research Organisation
Custom Manufacturing/Custom Synthesis
Intermediates Manufacturer

Santiago Chemikalie

  • CZ
  • 2023
    On CPHI since
  • 1 - 24
    Employees
Company types
Contract Research Organisation (CRO)
Contract Service
Primary activities
Chemical Development
Contract Manufacturer
Contract Research Organisation
Custom Manufacturing/Custom Synthesis
Intermediates Manufacturer

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