Ventilation and agitation are two means of supplying oxygen and nutrients to the microorganisms in the fermenter. The combination of the two together completes the mixing and mixing of the fermenter, which is the biggest feature of the fermenter mixing design.The compressed air is supplied to the microorganisms to dissolve oxygen through the gas distribution device. Mechanical agitation provides for bubble dispersion and macromixing and micromixing of the medium. However, both the aeration and agitation methods need to provide energy to complete the effect. Generally, compressed air accounts for about 60% of the mixed energy consumption, and mechanical agitation accounts for 40% of the energy consumption. In order to achieve the fermentation process effect. Designers should combine these two approaches to achieve the lowest energy consumption and the best process results.