Chlorobutanol Hemihydrate

Appearance: 
White crystal powder; it has special odor resembling camphor; Easy to sublimate. Soluble in ethanol, chloroform, ether or volatile oil, slightly soluble in water.
Application:
Used as a preservative in pharmaceuticals, the commonly used concentration is 0.5% (W/V).
Widely used as preservatives in ointment, ophthalmic preparations and veterinary injections such as Oxytocin, Colistin sulfate chlorogenic acid, Cephalexin, Tolfenamic Acid. and especially suitable for non-aqueous preparations.
Antifungal and antibacterial, effective against Gram-positive and Gram-negative bacteria and some fungi, such as Candida albicans and Pseudomonas aeruginosa.
The antibacterial activity is bacteriostatic rather than bactericidal. When the pH is greater than 5.5, the activity decreases significantly.